The New York Jets just cannot catch a break. But, boy, can their quarterback catch a cold! Here’s a look at the key injuries entering Week 2 of the NFL season:

Sam Darnold: What is this, the 1970s? Darnold has been diagnosed with the good ol’ “kissing disease” known as mononucleosis. All jokes aside, mono is nothing to trifle with, and the Jets are already saying Darnold is going to miss several weeks as he recovers. This is a massive blow to the Jets offense, which may also be without Le’Veon Bell (see below). Trevor Siemian will be under center for the forseeable future, so downgrade the entire Jets offense and look to stream whichever defense is facing them.

Le’Veon Bell: As if the news isn’t bad enough for the Jets, Bell is scheduled for an MRI on his shoulder and is clearly no guarantee to suit up on Monday. Perhaps the extra day will be enough for Bell to give it a go, but regardless, this is a huge opportunity for Ty Montgomery, especially with the Jets likely to go heavy on the ground to hide Trevor Siemian.

Quincy Enunwa: Suddenly, this is old Jets injury news, but it should be mentioned that Enunwa will miss the rest of the season with a neck injury, which really complicates things for the Jets. Jamison Crowder drew 17 targets in Week 1 and that number should only increase this week. Demaryius Thomas, just acquired from the Patriots this week, should be able to step in immediately and be a factor here.

Hunter Henry: The Chargers tight end who hasn’t seen much of the field the past couple of seasons is out again with a broken kneecap. The Chargers haven’t placed Henry on the IR, but he is still expected to miss several weeks. There is no Antonio Gates waiting in the wings this time, so expect Henry’s targets and production to get spread out among the likes of Keenan Allen and Austin Ekeler.

Derrius Guice: The injury bug has caught up with the young Redskins running back once again, and the second-year man is expected to miss a few weeks with an meniscus issue. This opens the door for Adrian Peterson, who was benched in Week 1, much to the dismay of his teammates. Named the starter in Week 2, it will be interesting to see how Peterson responds to this second chance. Expect an angry performance, to say the least.

Tyreek Hill: Karma is … you know. With Hill out 4-6 weeks with a collarbone injury, it sounds like the slack will be picked up by Mecole Hardman and D’Anthony Thomas. But let’s face it, the guys soaking up the production will be Travis Kelce and Sammy Watkins.

Mike Williams: Williams isn’t looking good for Week 2 for the Chargers, who signed a wide receiver off the street on Wednesday in anticipation of Williams not being available. Coupled with Hunter Henry being out, Austin Ekeler is looking like a stone-cold lock to soak up extra passing targets. But this makes the Chargers particularly vulnerable heading to Detroit.